County Hospital built at present site through the efforts of Dr. Benjamin Cory, San Jose's first medical practitioner.
1900's - 1910's
 First training program established - a school of nursing with 3 students.
 Dr. Doxey Wilson becomes the first intern at VMC.
 Dr. Wilson becomes the first full time Director of Medical Institution.
 Miss Merkle, RN, comes from Massachusetts General to serve as Superintendent of Nurses.
1930's - 1950's
 The Pediatric Unit was constructed.
 The Maternity Unit was constructed.
 Dr. Milton Chatton becomes Director of Medical Institution. Santa Clara Valley Medical Center becomes one of the first hospitals in the nation to be accredited by the Joint Commission for the Accreditation of Hospitals.
 Santa Clara Valley Medical Center's Pediatrics Department was established.
 First university affiliated residency program is established with Stanford.
1960's - 1970's
 Dr. Norman Nelson becomes Director of Medical Institution. Surgery Department becomes integrated with Stanford. A new Outpatient Department is completed.
 The Institute for Medical Research is formed.
1968 Demolition of the original hospital building occurs.
 A new, four story Rehabilitation Center is completed. The Department of Medicine's affiliation with Stanford begins. The first Medicine internships begin.
 Dr. Yvonne Russell becomes Director of Medical Institution. Joint recruiting with Stanford begins.
 Santa Clara Valley Medical Center celebrates its Centennial. The Primary Care Division is established in the Department of Medicine. Integrated Medicine fellowships with Stanford begin.
 Robert Sillen becomes Executive Director of Santa Clara Valley Medical Center.
1990's - future
 The West Wing opens with new Intensive Care Unit, Transitional Care Unit, Maternity, Primary Care Residency Program in the Department of Medicine begins.
 Robert Sillen becomes Executive Director of the newly combined Santa Clara Valley Health & Hospital System.
 The new Main Hospital Building at Santa Clara Valley Medical Center opens. Susan Murphy becomes Director of Santa Clara Valley Medical Center.
 SCVMC becomes the primary care provider for thousands of children being enrolled in the Children's Health Initiative (CHI), a first in the nation effort that used tobacco settlement money to provide healthcare coverage to kids without healthcare.
 Santa Clara County Board of Supervisors approves the construction of Valley Specialty Center, a new model for providing outpatient services more efficiently.
 Kim Roberts becomes the Chief Executive Officer of Santa Clara Valley Health & Hospital System, and Michael Skehan becomes Executive Director of Santa Clara Valley Medical Center.
 The new Valley Specialty Center, ambulatory care clinic, including the Cancer and Diabetes Center, opens.
 Linda M. Smith becomes CEO of SCVMC.
 Sylvia Gallegos, Deputy County Executive, becomes CEO of SCVHHS.
 Rene Santiago, Deputy County Executive, becomes CEO of SCVHHS.
 Paul Lorenz becomes CEO of SCVMC.
 Benita McLarin becomes Chief Operating Officer for SCVMC.
 Women and Children’s Health Services initiative started.