This study will begin recruitment soon. The main purpose of this multi-site research study, sponsored by Neofect and led by the Stanford Stroke Center, is to examine the implementation of the Smart Glove in rehabilitation for stroke survivors and to see how effective the Smart Glove is at helping to improve hand and arm function as well as quality of life post stroke. The Smart Glove is a plastic glove that straps to the affected hand and is connected to a computer to play games that mimic hand rehabilitation exercises. Movement is detected by the sensors in the glove and is recorded by the computer.
The target for enrolment is 80 participants across four sites. Participants are recruited from the inpatient rehabilitation units at SCVMC shortly after their stroke. Participants are then randomly assigned to receive either usual care or usual care plus the Smart Glove for the duration of this 24-week study. Participants who do not receive the Smart Glove during the study are offered use of a Smart Glove for six weeks following their completion of the study.
The Time Burden of Bladder and Bowel Care in Persons with Spinal Cord Injury
This study is currently recruiting participants who receive care at SCVMC. The goal of the study is to understand how much time persons with SCI spend attending to their bladder and bowel needs and to evaluate how time spent performing Clean Intermittent Catheterization for bladder management changes as a patients live with their condition longer. Bladder and bowel care time burden will be assessed using a stop watch in either the hospital, clinic, or home setting. Using this information, we hope to quantify the “time burden” to perform bladder and bowel care for persons with SCI, shed light on factors influencing satisfaction with current bladder care, and identify reasons for choosing alternative bladder management strategies.
For more information, please contact Michael Prutton at;
Northern California Traumatic Brain Injury Model System
The Traumatic Brain Injury Model Systems (TBIMS) National Database is a prospective, longitudinal study funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in the U.S. Department of Health and Human Services. The TBIMS is actively recruiting study participants at multiple centers across the U.S. Its purpose is to assess recovery and outcomes following multi-disciplinary treatment in acute neurotrauma and inpatient rehabilitation. Our center is currently enrolling participants during their rehabilitation stay (Form I) and completing follow-up interviews (Form II) at years 1, 2, 5, and every 5 years after their date of injury. As of June 2020, our center has enrolled over 870 participants and is completing follow-up interviews with participants who are up to 35 years post-injury. In addition to providing direct health care services, the TBIMS centers play an important role in providing high-quality treatment and research serving persons with TBI, their families, and the communities in which they live.
For more information on this study, please contact Jussely Morfin at;
Northern California Spinal Cord Injury Model System
The Spinal Cord Injury Model Systems (SCIMS) National Database is a prospective, longitudinal study funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in the U.S. Department of Health and Human Services. The National Database includes about 6% of new SCI cases, and has data on thousands of individuals treated in the United States with SCI since 1970. Our center is one of 19 centers currently doing follow-up research (Form II) in areas of rehabilitation, health & wellness, emotional distress, technology, and re-hospitalization. The purpose of the study is to collect long-term outcomes from individuals who had an SCI, after their discharge from the SCVMC healthcare system. As of June 2020, our center has followed over 2,400 participants, some of whom are up to 45 years post-injury.
For more information on this study, please contact Cria-May Khong at;
ASTERIAS - AST-OPC1-01/02
This study is closed to enrolment and is currently in long term follow up. The AST-OPC1-01 clinical trial, “A Phase 1/2a Dose Escalation Study of AST-OPC1 in Subjects with Subacute Cervical Spinal Cord Injury”, studied the safety and effectiveness of oligodendrocyte progenitor cells derived from human embryonic stem cells injected directly into the spinal cord of patients with cervical spinal cord injury. Participants were evaluated for neurological improvements for one year post-injection. The safety follow-up will continue for 15 years under the companion study AST-OPC1-02, “A Long-term Follow-up Study of Subjects with Cervical Spinal Cord Injuries Who Received AST-OPC1 in Protocol AST-OPC1-01”.
SCVMC was the first site in the United States injecting 20 million stem cells into the spinal cord of a patient with ASIA A or ASIA B impairments. SCVMC is a leading enrollment site for this national clinical trial.
The TRACK-SCI collaborative is a unique partnership between the VA Palo Alto, Zuckerberg San Francisco General Hospital (ZSFG), UCSF Brain and Spinal Injury Center (BASIC), and Santa Clara Valley Medical Center (SCVMC). This partnership provides an exceptional platform for the discovery and testing of acute, critical care practices that optimize recovery among individuals who have experienced a spinal cord injury. The aim of this collaboration is to provide data for driving evidence-based recommendations and guidelines for the treatment of acute SCI.
For more information, please contact Arshad Ali at;