Research Projects

Tele-psychology intervention for individuals with spinal cord injury and depression

Psychotherapy provided remotely is called tele-psychology and this study will provide cognitive behavioural therapy (CBT) through Facetime on an iPad to persons with spinal cord injury (SCI) and depression after injury. Half of the enrolled and eligible participants will receive the tele-psychology intervention, while the other half will receive routine care managed by their doctor. Participants in the therapy group will receive 10 tele-psychology sessions over 12 weeks, provided by a study psychologist. The study team will compare results once therapy is completed and then again 12-weeks later to pre-therapy measures between the CBT therapy group and those who receive standard of care instead of CBT, to see if the intervention is efficacious. We hope to show that individuals receiving CBT will have reduced depressive and anxiety symptoms and increased quality of life at 12 and 24 weeks post-baseline compared to individuals receiving usual care.

For more information on this study, please contact Cria-May Khong at;
[email protected] or 408-885-4177 posting


Virtual Reality Glove for Hand and Arm Rehabilitation After Stroke (vREHAB) ​

This study is open to enrollment. The main purpose of this multi-site research study, sponsored by Neofect and led by the Stanford Stroke Center, is to examine the implementation of the Smart Glove in rehabilitation for stroke survivors and to see how effective the Smart Glove is at helping to improve hand and arm function as well as quality of life post stroke. The Smart Glove is a plastic glove that straps to the affected hand and is connected to a computer to play games that mimic hand rehabilitation exercises. Movement is detected by the sensors in the glove and is recorded by the computer. 

The target for enrolment is 80 participants across four sites. Participants are recruited from the inpatient rehabilitation units at SCVMC shortly after their stroke. Participants are then randomly assigned to receive either usual care or usual care plus the Smart Glove for the duration of this 24-week study. Participants who do not receive the Smart Glove during the study are offered use of a Smart Glove for six weeks following their completion of the study.

For more information, please contact Michael Prutton at;
[email protected] or 408-885-3961 posting​


The Time Burden of Bladder and Bowel Care in Persons with Spinal Cord Injury

This study is currently recruiting participants who receive care at SCVMC. The goal of the study is to understand how much time persons with SCI spend attending to their bladder and bowel needs and to evaluate how time spent performing Clean Intermittent Catheterization for bladder management changes as a patients live with their condition longer. Bladder and bowel care time burden will be assessed using a stop watch in either the hospital, clinic, or home setting. Using this information, we hope to quantify the “time burden” to perform bladder and bowel care for persons with SCI, shed light on factors influencing satisfaction with current bladder care, and identify reasons for choosing alternative bladder management strategies.  

For more information, please contact Michael Prutton at;
[email protected] or 408-885-3961


Northern California Traumatic Brain Injury Model System

The Traumatic Brain Injury Model Systems (TBIMS) National Database is a prospective, longitudinal study funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in the U.S. Department of Health and Human Services. The TBIMS is actively recruiting study participants at multiple centers across the U.S. Its purpose is to assess recovery and outcomes following multi-disciplinary treatment in acute neurotrauma and inpatient rehabilitation. Our center is currently enrolling participants during their rehabilitation stay (Form I) and completing follow-up interviews (Form II) at years 1, 2, 5, and every 5 years after their date of injury. As of June 2020, our center has enrolled over 870 participants and is completing follow-up interviews with participants who are up to 35 years post-injury. In addition to providing direct health care services, the TBIMS centers play an important role in providing high-quality treatment and research serving persons with TBI, their families, and the communities in which they live.

For more information on this study, please contact Jussely Morfin at;
[email protected] or call 408-793-1819​.

TBIMS Data Center
TBIMS InfoSheet


Sistema modelo de la lesión cerebral traumática del norte de california

La Base de Datos Nacional de los Sistemas Modelo de la Lesión Cerebral Traumática (TBIMS, por sus siglas en inglés) es un estudio prospectivo y longitudinal financiado por el Instituto Nacional de la Investigación sobre la Discapacidad, Vida Independiente y Rehabilitación (NIDILRR, por sus siglas en inglés) en el Departamento de Salud y Servicios Humanos de los Estados Unidos. El TBIMS está reclutando activamente a los participantes de estudio a lo largo y ancho de los Estados Unidos. Su propósito es evaluar la recuperación y los resultados después del tratamiento multidisciplinario del neurotrauma agudo y la rehabilitación hospitalaria. En la actualidad, nuestro centro está inscribiendo a los participantes durante su estancia de rehabilitación (Formulario l) y está llevando a cabo las entrevistas de seguimiento (Formulario II) a un año, dos, cinco, y cada cinco años después de su fecha de lesión. A fecha de junio de 2020, nuestro centro ha inscrito a más de 870 participantes y está realizando las entrevistas de seguimiento con los participantes que han cumplido hasta 35 años después de su lesión. Además de prestar los servicios directos de atención de salud, los centros de TBIMS desempeñan un papel importante en proporcionar tratamiento de alta calidad e investigación atendiendo a las personas con lesión cerebral traumática, a sus familiares, y a las comunidades donde ellos viven.

Para obtener más información acerca de este estudio, por favor póngase en contacto con Jussely Morfin enviando un correo electrónico a;
[email protected] o llamando al 408-793-1819​

Centro de Datos de TBIMS
Hoja Informativa de TBIMS


Northern California Spinal Cord Injury Model System

The Spinal Cord Injury Model Systems (SCIMS) National Database is a prospective, longitudinal study funded by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in the U.S. Department of Health and Human Services. The National Database includes about 6% of new SCI cases, and has data on thousands of individuals treated in the United States with SCI since 1970. Our center is one of 19 centers currently doing follow-up research (Form II) in areas of rehabilitation, health & wellness, emotional distress, technology, and re-hospitalization. The purpose of the study is to collect long-term outcomes from individuals who had an SCI, after their discharge from the SCVMC healthcare system.  As of June 2020, our center has followed over 2,400 participants, some of whom are up to 45 years post-injury. 

For more information on this study, please contact Cria-May Khong at;
[email protected] or call 408-885-4177.

SCIMS Data Center
SCIMS Facts & Figures​



This study is closed to enrolment and is currently in long term follow up. The AST-OPC1-01 clinical trial, “A Phase 1/2a Dose Escalation Study of AST-OPC1 in Subjects with Subacute Cervical Spinal Cord Injury”, studied the safety and effectiveness of oligodendrocyte progenitor cells derived from human embryonic stem cells injected directly into the spinal cord of patients with cervical spinal cord injury. Participants were evaluated for neurological improvements for one year post-injection. The safety follow-up will continue for 15 years under the companion study AST-OPC1-02, “A Long-term Follow-up Study of Subjects with Cervical Spinal Cord Injuries Who Received AST-OPC1 in Protocol AST-OPC1-01”.

SCVMC was the first site in the United States injecting 20 million stem cells into the spinal cord of a patient with ASIA A or ASIA B impairments. SCVMC is a leading enrollment site for this national clinical trial. 

For more information, please contact Arshad Ali at
[email protected] or 408-885-3963. posting​



The TRACK-SCI collaborative is a unique partnership between the VA Palo Alto, Zuckerberg San Francisco General Hospital (ZSFG), UCSF Brain and Spinal Injury Center (BASIC), and Santa Clara Valley Medical Center (SCVMC). This partnership provides an exceptional platform for the discovery and testing of acute, critical care practices that optimize recovery among individuals who have experienced a spinal cord injury. The aim of this collaboration is to provide data for driving evidence-based recommendations and guidelines for the treatment of acute SCI. 

For more information, please contact Arshad Ali at;
[email protected] or 408-885-3963.